Cefixime

C. diff Risk

Medium

Oral Bioavailability

Excellent

Approximate Cost

4$/d

Dosing

General Pediatric

8 mg/kg/24h PO divided q12-24h
Maximum: 400 mg/24h

Renal

Renally cleared, requires dosage adjustment with changes in renal function. Consult a pharmacist for renal dosing.

General Information

Common Usage

UTI, gonorrhoea

Adverse Effects

  • Allergy (immediate & delayed), structurally unrelated to most B-lactams,

  • Positive Coombs

  • Cytopenias

  • GI upset, diarrhea

  • Abnormal liver enzymes

Pharmacology

Antimicrobial class: 3rd Generation Cephalosporin