Monitor QTc in patients with increased risk.
Prolongation of QTc interval.
Orally administered azithromycin, when given in the first 6 weeks of life, is associated with increased risk of infantile hypertrophic pyloric stenosis (IHPS), therefore clinicians need to weigh benefits and risks when considering its use. Azithromycin however remains the drug of choice for treatment or prophylaxis of pertussis in very young infants. Cases of IHPS in young infants who have been treated with a macrolide antibiotic should be reported to Health Canada.
While less risk of interaction compared to other macrolides, several potential CYP450 interactions may occur; consult a pharmacist for for more details.
Avoid concurrent use with other drugs that prolong QTc.
Concentration: 40 mg/mL
Taste: bitter
Not all strengths of oral liquids are listed nor are available on IWK formulary
Antimicrobial class: Macrolide
Average serum half life:
Route of Elimination: