Antimicrobials
Ampicillin

Ampicillin

Low
N/A
$35/day

General Information

Pathogen directed therapy for CNS, intravascular, intraabdominal, urinary and other infections especially Enterococcus and Listeria. As part of empiric therapy for early onset sepsis in neonates.

  • Renal
  • Liver function
  • CBC with differential
  • Allergy and rash
  • EBV related rash (not allergy)
  • Rare: Cytopenias, +ve Coombs

Antimicrobial class: Aminopenicillin

Average serum half life:

  • Neonates
    • PNA 2-7 days: 4 hours
    • PNA 8-14 days: 2.8 hours
    • PNA 15-30 days: 1.7 hours
  • Pediatrics: 1-1.8 hours
  • Anuric patients: 8-20 hours

Route of Elimination:

  • 90% excreted unchanged in urine within 24 hours
  • Excreted in bile