$1/day (liquid extremely expensive)
Usual dose: 500 mg PO q6h
12.5-25 mg/kg/dose q6h
12.5-25 mg/kg/dose q8h
PNA-days 7 - 21
12.5-25 mg/kg/dose q12h
PNA-days 0 - 7
Renally cleared, requires dosage adjustment with changes in renal function. Consult a pharmacist for renal dosing.
Uncomplicated skin and soft tissue infection, osteomyelitis, MSSA infections
Allergy/rash (immediate or delayed), cephalexin and amoxicillin have the same side chain, hence cross -allergenicity may occur
Can cause positive Coombs, cytopenias, eosinophilia
Concentration: 50 mg/mL
Taste: very palatable
Not all strengths of oral liquids are listed nor are available on IWK formulary
500 mg tablet
Tablets and capsules are preferred especially over an unpleasant tasting liquid.
Not all strengths of oral tablets/capsules are listed and they are not all available on the IWK formulary.
Antimicrobial class: First generation cephalosporin - oral
Average serum half life:
Neonates: 5 hours.
Children 3 to 12 months: 2.5 hours.
Adults: 0.5-1.2 hours
Route of Elimination: 80% to 100% of dose excreted as unchanged drug in urine within 8 hours