Gentamicin
General Pediatric

General Pediatric

Extended Interval Dosing (Preferred Dosing)

Exceptions to use of extended interval dosing: 

  • renal dysfunction at baseline (consider alternate antibiotic) 
  • synergistic dosing of aminoglycosides with beta-lactams for gram positive infections (see below)

7 mg/kg/dose IV q24h Maximum: 400 mg/24h prior to levels

Conventional Dosing

2.5 mg/kg/dose IV q8h

Synergistic dosing of aminoglycosides with beta-lactams for gram positive infections

1 mg/kg/dose IV q8h