Acyclovir - Neonatal Dosing
Patients 0 to 7 days (post-natal age) AND less than or equal to 2000 grams (2 kg)
Patients 8 days or greater (post-natal age) AND less than or equal to 2000 g (2 kg)
Patients greater than 2000 grams (2 kg) regardless of post-natal age
Neonatal suppressive therapy following parenteral therapy for neonatal HSV CNS disease (suppressive therapy may also be offered for neonatal HSV disseminated or SEM (skin, eye and mouth) disease, consult Infectious Diseases. Monitor monthly CBC, urea, creatinine and weight (for dose adjustment).
300 mg/m²/dose PO q8h X 6 months