Renally cleared, requires dosage adjustment with changes in renal function. Consult a pharmacist for renal dosing.
Treatment and prophylaxis of influenza
GI upset common
Rare - Stevens Johnson Syndrome
Neuropsychiatric side effects reported
Treatment should ideally begin within 48 hours
Antimicrobial class: Antiviral - neuraminidase inhibitor
Average serum half life: No pediatric data available.
Adult: Oseltamivir phosphate: 1-3 hours, oseltamivir carboxylate: 6-10 hours
Route of Elimination: Hepatically metabolixed to >99% of oseltamivir carboxylate (active metabolite) is eliminated by renal excretion via glomerular filtration and tubular secretion