Renally cleared, requires dosage adjustment with changes in renal function. Consult a pharmacist for renal dosing.
Treatment and prophylaxis of influenza
Neuropsychiatric side effects reported in Japan
Concentration: 6 mg/mL
Not all strengths of oral liquids are listed nor are available on IWK formulary
75 mg capsule
Tablets and capsules are preferred especially over an unpleasant tasting liquid.
Not all strengths of oral tablets/capsules are listed and they are not all available on the IWK formulary.
Treatment should ideally begin within 48 hours
Antimicrobial class: Antiviral - neuraminidase inhibitor
Average serum half life: No pediatric data available.
Adult: Oseltamivir phosphate: 1-3 hours, oseltamivir carboxylate: 6-10 hours
Route of Elimination: Hepatically metabolixed to >99% of oseltamivir carboxylate (active metabolite) is eliminated by renal excretion via glomerular filtration and tubular secretion