Only indication is in the therapy of C. difficile infection, particularly recurrent or severe disease
Possibility of accumulation in severe renal dysfunction; consider checking a vancomycin level in dialysis patients
Avoid concurrent administration of oral vancomycin and bile acid sequestrants (may diminish therapeutic effect of vancomycin).
No oral absorption. May increase vancomycin resistant enterococci colonization in the gut
Antimicrobial class: glycopeptide
Route of Elimination: Primarily feces as limited absorption
Average serum half life: serum half life not available due to low systemic absorption