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Guidelines
Pathogens
Antimicrobials
Low
Moderate
$0.50/day
Use with caution; excretion is prolonged in patients with renal impairment. Consult with a pharmacist for dosing in renal impairment.
Streptococcal infections and therapy of documented susceptible infection not requiring parenteral therapy (i.e. upper respiratory tract)
Prophylaxis for asplenia
Rheumatic fever
Monitor for allergy
Allergy (anaphylaxis) and other rash
Cytopenias, Positive Coombs, Eosinophilia
Serum sickness
Acute interstitial nephritis
Concentration: 60 mg/mL Taste: not very palatable, unpleasant taste Not all strengths of oral liquids are listed nor are available on IWK formulary
300 mg tablet Tablets and capsules are preferred especially over an unpleasant tasting liquid. Not all strengths of oral tablets/capsules are listed and they are not all available on the IWK formulary.
Antimicrobial class: Penicillin
Average serum half life: No pediatric data. Adults: 30 minutes; prolonged in patients with renal impairment
Route of Elimination: Penicillin V and its metabolites are excreted in urine