Antimicrobials
Penicillin VK (oral)

Penicillin VK (oral)

Low
Moderate
$0.50/day

Spectrum of Activity

General Information

  • Streptococcal infections and therapy of documented susceptible infection not requiring parenteral therapy (i.e. upper respiratory tract)
  • Prophylaxis for asplenia
  • Rheumatic fever

Monitor for allergy

  • Allergy (anaphylaxis) and other rash
  • Cytopenias, Positive Coombs, Eosinophilia
  • Serum sickness
  • Acute interstitial nephritis

Concentration: 60 mg/mL Taste: not very palatable, unpleasant taste Not all strengths of oral liquids are listed nor are available on IWK formulary

300 mg tablet Tablets and capsules are preferred especially over an unpleasant tasting liquid. Not all strengths of oral tablets/capsules are listed and they are not all available on the IWK formulary.

Antimicrobial class: Penicillin

Average serum half life: No pediatric data. Adults: 30 minutes; prolonged in patients with renal impairment

Route of Elimination: Penicillin V and its metabolites are excreted in urine