Renally cleared, requires dosage adjustment with changes in renal function. Consult a pharmacist for renal dosing.
IV formulation contains sulfobutyl ether beta-cyclodextrin (SBECD) which may accumulate in renal insufficiency.
In pediatric patients
Many via CYP450- suggest review interactions with pharmacist.
Risk when combining with other QTc prolonging agents
Concentration: 40 mg/mL
Not all strengths of oral liquids are listed nor are available on IWK formulary
50 mg tablet
200 mg tablet
Tablets and capsules are preferred especially over an unpleasant tasting liquid.
Not all strengths of oral tablets/capsules are listed and they are not all available on the IWK formulary.
Antimicrobial class: Triazole antifungal, second generation
Average serum half life: Variable and dose dependent.
Route of Elimination: Urine (<2% as unchanged drug)