Pseudomonal and other gram negative infections, inhaled form used in cystic fibrosis
Antimicrobial class: Aminoglycoside
Average serum half life: Neonates: ≤1200 g: 11 hours, >1,200 g: 2 to 9 hours. Infants: 4 ± 1 hour. Children: 2 ± 1 hour. Adolescents: 1.5 ± 1 hour Adults: IV: 1-2 hours; directly dependent upon glomerular filtration rate Adults with impaired renal function: 5- 70 hours
Route of Elimination: With normal renal function, 93% of dose excreted in urine within 24 hours