Tobramycin - Neonatal Dosing

EXTENDED INTERVAL INITIAL DOSING. Dosage adjustments are made based on serum concentrations, clinical response and renal function (see "Drug Monitoring").

Post natal age less than or equal to 7 days

5 mg/kg/dose IV q48h

Post natal age 8 to 28 days

4 mg/kg/dose IV q36h

Post natal age greater than or equal to 29 days

4 mg/kg/dose IV q24h

EXTENDED INTERVAL INITIAL DOSING. Dosage adjustments are made based on serum concentrations, clinical response and renal function (see "Drug Monitoring").

Post natal age less than or equal to 7 days

4.5 mg/kg/dose IV q36h

Post natal age greater than or equal to 8 days

4 mg/kg/dose IV q24h

EXTENDED INTERVAL INITIAL DOSING. Dosage adjustments are made based on serum concentrations, clinical response and renal function (see "Drug Monitoring").

4 mg/kg/dose IV q24h