cefOXitin

C. diff Risk

Medium

Oral Bioavailability

NA

Approximate Cost

Spectrum Of Activity

Dosing

1-2 g IV q6-8h

Post natal age greater than 22 days40 mg/kg/dose IV q6h

Post natal age 7 to 21 days40 mg/kg/dose IV q8h

Post natal age less than 7 days40 mg/kg/dose IV q12h

Renally cleared, requires dose adjustment with changes in renal function. Consult a pharmacist for renal dosing

General Information

Adverse Effects

  • Allergy (immediate and delayed)

  • Positive Coombs

  • Cytopenias

  • GI upset, diarrhea

  • Abnormal liver enzymes

Pharmacology

Antimicrobial class: 2nd Generation Cephalosporin