Doses be adjusted based on serum drug level monitoring.
Higher dosing may be required to achieve higher desired serum concentrations in severe infections.
40-60 mg/kg/24h IV divided q6-8h
Maximum: 4000 mg/ 24 h prior to levels.
Febrile Neutropenia (Oncology Patients)
Meningitis, Greater than or equal to 4 weeks of age
Cerebral Abscess/Subdural Empyema