400 mg IV/PO daily
No dose adjustment
Monitor QTc in patients with increased risk
CNS toxicity including confusion, psychosis
Tendinopathy and rupture
Weakness exacerbation in myasthenia gravis
QTc prolongation - Increased risk with other agents that prolong QTc
Divalent cations including Ca, Mg - decreased absorption
Warfarin - increased INR
Rifampin - decrease moxifloxacin levels
Low urinary drug levels - do not use to treat UTI.
May exacerbate muscle weakness in persons with myasthenia gravis. Avoid Use.
Antimicrobial class: Fluoroquinolone
Pregnancy category: C