Antimicrobials
Fosfomycin

Fosfomycin

Restricted

Low
Moderate

Spectrum of Activity

Dosing

General Information

Restricted to treatment of acute uncomplicated cystitis caused by susceptible organisms with demonstrated resistance and/or intolerance to all other oral agents.

DO NOT use for pyelonephritis or bacteremia as insufficient systemic drug levels.

  • GI upset, esp. diarrhea
  •  Headache
  •  Eosinophilia, neutropenia
  •  Hypokalemia

No significant

IV formulation not available in Canada

Antimicrobial class: Phosphonic acid derivative

Pregnancy category: B