Gentamicin
Renal

Renal

Dosing Notes

Obese patients are dosed according to Dosing Body Weight (DBW).

Consult pharmacist or refer to "Additional Information" section for details.

Round to nearest 20 mg

Not On Dialysis: Extended Interval Dosing (CrCl)

60+ mL/min

7 mg/kg IV q24h

40 - 59 mL/min

7 mg/kg IV q36h

0 - 40 mL/min

Refer to conventional dosing

Not On Dialysis: Conventional Dosing (CrCl)

80+ mL/min

2 mg/kg IV q8h

50 - 79 mL/min

2 mg/kg IV q12h

20 - 49 mL/min

2 mg/kg IV q24h and consult pharmacist

0 - 20 mL/min

2 mg/kg IV once and consult pharmacist

Not On Dialysis: Synergy dosing

Staphylococcal and Enterococcal Infections

1 mg/kg IV q8h

Streptococcal Infections

3 mg/kg IV q24h

Synergy dosing is based on Ideal Body Weight (IBW).

Consult pharmacist or refer to "Additional Information" section for details.

Intermittent Hemodialysis

2 mg/kg IV once then 1 mg/kg IV qHD Consult pharmacist

Synergy dosing: 1 mg/kg IV qHD

CVVHDF

3 mg/kg IV load, then 2 mg/kg IV q24-48h Consult pharmacist

Synergy dosing: 1 mg/kg IV q24h

PD

2 mg/kg IV once and consult pharmacist