Acyclovir - Renal Dosing

10+ mL/min

400 mg PO TID

<10 mL/min or HD

400 mg PO BID - give dose after dialysis on dialysis days

PD

400 mg PO BID

25+ mL/min

800 mg PO 5 times per day

10 - 25 mL/min

800 mg PO TID

<10 mL/min or HD

800 mg PO BID - give dose after dialysis on dialysis days

PD

800 mg PO BID

50+ mL/min

10 mg/kg q8h

25 - 50 mL/min

10 mg/kg q12h

10 - 24 mL/min

10 mg/kg q24h

<10 mL/min or HD

5 mg/kg q24h - give dose after dialysis on dialysis days

CVVHDF

10 mg/kg q12h

PD

5 mg/kg q24h