Meropenem

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Restricted

C. diff Risk

Medium

Oral Bioavailability

NA

Approximate Cost

Dosing

High dose: 2000 mg IV q8h

Standard dose: 500 mg IV q6h

General Information

Adverse Effects

Immediate and delayed-type allergy

GI disturbanceCytopenias, positive Coombs

Liver enzyme abnormalities

Major Interactions

Valproic acid - carbapenems decrease valproate levels and may decrease seizure threshold

Pharmacology

Antimicrobial class: carbapenem

Pregnancy category: B