Colistin

Restricted
Restricted

C. diff Risk

Low

Oral Bioavailability

NA

Approximate Cost

Dosing

ALL DOSING IS FOR COLISTIN BASE
Loading dose: 4 mg/kg IV once (use lower of ideal or actual body weight)
Maintenance dose: 150 mg IV q12h

General Information

Common Usage

IV Colistin should generally be used in combination therapy (meropenem or imipenem). Infectious Diseases consultation recommended.

Additional Information

Colistin equivalency conversion:
30 mg colistin base activity = 80 mg colistimethate = 1 million IU colistin