Prophylaxis/maintenance dose: 5 mg/kg IV q24h
Treatment/induction dose: 5 mg/kg IV q12h
CBC with differential twice weekly. Serum creatinine once weekly.
-May cause blood dyscrasias: granulocytopenia, anemia, and thrombocytopenia. Usually within first 1-2 weeks of treatment. Generally resolves within 3-7 days of discontinuation.
Antimicrobial class: Antiviral, binds DNA polymerase to inhibit viral DNA synthesis.
Pregnancy category: C - animal studies have demonstrated carcinogenic and teratogenic effects.