Antimicrobials
Penicillin VK (Oral)

Penicillin VK (Oral)

Low
Good (70 to 90%)
<$

Spectrum of Activity

Dosing

General Information

  • Streptococcal infections and therapy of documented susceptible infection not requiring parenteral therapy (i.e. upper respiratory tract)
  • Prophylaxis after rheumatic fever
  • Monitor for allergy
  • Periodic CBC, SCr
  • Allergy (anaphylaxis) and other rash
  • Cytopenias, Positive Coombs, Eosinophilia
  • Serum sickness
  • Acute interstitial nephritis

Prisma Health Inpatient Formulary
Solution: 250 mg/5 mL

Other Available Outpatient Strengths
Solution: 125 mg/5 mL

Prisma Health Inpatient Formulary
Tablet: 250 mg, 500 mg

Antimicrobial class: Penicillin

Average serum half life:

  • No pediatric data
  • Adults: 30 minutes; prolonged in patients with renal impairment

Biliary Pentration: Detectable but lower than serum

Route of Elimination: Penicillin V and its metabolites are excreted in urine