Skin and soft tissue infection
Methicillin resistant staphylococcus aureus infections
Community acquired pneumonia
Malaria prophylaxis
Zoonoses
Skin and soft tissue infections
Rickettsia and other tick-borne diseases
Chlamydia
Mycoplasma
GI upset and erosive esophagitis
Photosensitivity rash
Teeth staining (less than tetracycline)
Prisma Health Inpatient Formulary
Suspension (monohydrate): 25 mg/5 mL
Prisma Health Inpatient Formulary
Capsule (hyclate): 100 mg
Other Available Outpatient Strengths
Capsule (hyclate): 50 mg
Capsule (monohydrate): 50 mg, 75 mg, 100 mg, 150 mg
Delayed-release capsule (monohydrate): 40 mg
Delayed-release tablet (hyclate): 50 mg, 60 mg, 75 mg, 80 mg, 100 mg, 150 mg, 200 mg
Tablet (hyclate): 20 mg, 50 mg, 75 mg, 100 mg, 150 mg
Tablet (monohydrate): 50 mg, 75 mg, 100 mg, 150 mg
Avoid iron, magnesium, calcium, and dairy products for at least one hour before or two hours after doxycycline administration
Take with food to lessen nausea
Take with lots of water and not before bed to decrease occurence of esophagitis
Antimicrobial class: Tetracycline
Pregnancy category: D
Average serum half life: 18 hours
Biliary penetration: Good
CSF penetration: Poor
Lung penetration: Good
Urine penetration: Good
Route of Elimination: In the urine (40%) and feces (30%)
Metabolism: Partially inactivated in GI tract by chelate formation