Cefixime

C. diff Risk

Medium

Oral Bioavailability

Moderate

Approximate Cost

Dosing

Adult

400mg PO daily

General Information

Common Usage

Cefixime is often used in the treatment of gonococcal infections in select populations given emerging resistance.

Adverse Effects

  • Allergy/rash

  • Positive Coombs test

  • Cytopenias

  • Gastrointestinal intolerance

  • Elevated liver enzymes

  • Clostridium difficile associated diarrhea

Pharmacology

Antimicrobial class: 3rd Generation Cephalosporin

Pregnancy category: B

Average serum half life: 3 hours