Cefoxitin

C. diff Risk

Medium

Oral Bioavailability

NA

Approximate Cost

Dosing

Adult

Usual dosing
2g IV q6-8h

General Information

Adverse Effects

  • Allergy/rash

  • Positive Coombs test

  • Cytopenias

  • Gastrointestinal intolerance

  • Abnormal liver enzymes

  • Clostridium difficile associated diarrhea

Pharmacology

Antimicrobial class: 2nd Generation Cephalosporin

Pregnancy category: B

Average serum half life: 40-60 min

Lung penetration: Therapeutic

Urine penetration: Therapeutic

Biliary penetration: Therapeutic

CSF penetration: Poor

Route of Elimination: Urinary