1g IV q24h
Must be approved by Infectious Diseases
Restricted for usage by infectious disease service, vascular surgery and general surgery
Targeted therapy of ESBL infections and other resistant Gram negative infections.
Empiric therapy when broad spectrum of carbapenems is desired without the need for anti-pseudomonal activity.
Immediate and delayed-type allergy
Cytopenias, eosinophilia, positive Coombs
Liver enzyme abnormalities
Seizure risk lower than other carbapenems
Must be approved by Infectious Diseases.
Antimicrobial class: Carbapenem
Pregnancy category: B
Average serum half life: 4 hours
Urine penetration: Therapeutic
Lung penetration: Therapeutic
Biliary penetration: Moderate