Ceftazidime

C. diff Risk

Medium

Oral Bioavailability

NA

Approximate Cost

Dosing

Adult

Usual dosing
1-2g IV q8h

General Information

Common Usage

Ceftazidime is third generation cephalosporin with broad Gram negative coverage including coverage of Pseudomonas spp. and is generally used for nosocomial infections.

Ceftazidime lacks Gram positive activity compared to other cephalosporins.

Adverse Effects

  • Allergy/rash

  • Gastrointestinal intolerance

  • Clostridium difficile associated diarrhea

Major Interactions

No significant interactions

Pharmacology

Antimicrobial class: 3rd generation Cephalosporin

Pregnancy category: B

Average serum half life: 2 hours

Urine penetration: Therapeutic

CSF penetration: Therapeutic

Biliary penetration: Moderate

Lung penetration: Therapeutic