Cephalexin

C. diff Risk

Medium

Oral Bioavailability

Moderate

Approximate Cost

Dosing

Usual dose
500mg PO QID

General Information

Common Usage

Cephalexin is commonly used in the treatment of skin and soft tissue infections.

Adverse Effects

  • Allergy/rash

  • Positive Coombs test

  • Cytopenias

  • Hepatic & renal laboratory abnormalities

  • Clostridium difficile associated diarrhea

Major Interactions

Increases metformin levels

Pharmacology

Antimicrobial class: First Generation Cephalosporin.

Pregnancy category: B

Biliary penetration: Moderate

CSF penetration: Poor

Lung penetration: Moderate

Urine penetration: Therapeutic