Usual dose 2g IV q4-6h Meningitis OR Infective Endocarditis OR Osteomyelitis 2g IV q4h
Ampicillin is commonly used as pathogen directed therapy for intravascular, intra-abdominal and urinary infections secondary to certain Enterococcus spp.
Ampicillin is used as empiric therapy for bacterial meningitis if risk factors for Listeria monocytogenes are present.
Allergic reactions, rash
Clostridium difficile associated diarrhea
Allopurinol - increased risk of rash
Patients with infectious mononucleosis secondary to EBV and given amoxicillin or ampicillin may develop a rash and this is not indicative of a true allergy.
Antimicrobial class: Aminopenicillin
Pregnancy category: B
Average serum half life: 1 hour
Biliary penetration: Therapeutic
CSF penetration: Therapeutic
Lung penetration: Therapeutic
Urine penetration: Therapeutic