Hospital Formulary Status Yes (PO solid, PO powder for susp)
In-Hospital Cost will be updated
PharmaCare Formulary Status Yes (PO solid, PO susp)
SA None
PharmaCare Coverage 250mg PO - $0.4452/tab 500mg PO - $0.8983/tab 500mg XL PO - $1.3578/tab 125mg/5ml PO susp recon - $0.2211/ml 250mg/5ml PO susp recon - $0.4318/ml
Outpatient Cost 250mg PO - $0.45-0.75/tab 500mg PO - $2.01-2.94/tab 500mg XL PO - $1.42-1.61/tab 125mg/5ml PO susp recon - $0.22-0.24/ml 250mg/5ml PO susp recon - $0.43-0.47/ml
Monitor QTc in patients with increased risk
Gastritis (PO and IV)
QT interval prolongation and CV mortality (PO and IV)
Hearing loss (mainly with IV)
Other
Recommend review of patient medications due to high frequency of significant interactions
Antimicrobial class: Macrolide
Pregnancy category: C
Very high tissue penetration and concentration intracellularly means in vivo activity may not be predicted by in vitro testing.
Average serum half life: 5.0 hr
Urine penetration: Poor
Lung penetration: Therapeutic
CSF penetration: Poor
Biliary penetration: Therapeutic