2 gm IV q8h (max 6 gm/day)
Skin and soft tissue infection (i.e. cellulitis).
Susceptible Staphylococcal, Streptococcal and Gram negative infections.
Allergy (immediate or delayed).
Can cause positive Coombs, cytopenias, and hepatic and renal laboratory abnormalities.
Probenecid - prolonged half-life. Drug interaction has been used therapeutically to give once daily cefazolin
Antimicrobial class: 1st Generation Cephalosporin
Pregnancy category: B
Average serum half life: 2.0
Biliary penetration: Therapeutic
CSF penetration: Poor
Lung penetration: Therapeutic
Urine penetration: Therapeutic