125mg po/ng/og q6h for 10-14 days.
250mg in 100mL of NS by rectal enema q6h
Only indication is in the therapy of C. difficile infection, particularly recurrent or severe disease
Possibility of accumulation in severe renal dysfunction.
Consider checking a vancomycin level in dialysis patients.
No oral absorption. May increase vancomycin resistant enterococci colonization in the gut.
Cost listed above reflects oral liquid. Capsules are almost 10X more costly
Antimicrobial class: glycopeptide
Pregnancy category: B
Average serum half life: 0.0
Urine penetration: None
CSF penetration: None
Biliary penetration: None
Lung penetration: None