1-2g IV q4-6h 2g IV q4h for meningitis or endocarditis
Pathogen directed therapy for CNS, intravascular, intraabdominal, urinary and other infections especially enterococcus and listeria
Allergy and rash as for all beta-lactams.
Note: EBV-related rash - not an allergy (morbilliform rash occurring 48 hours to weeks after initial amoxicillin exposure in patients with Epstein Barr Virus does not appear to be a true drug allergy).
Rare: cytopenias, +ve Coombs
Allopurinol, methotrexate, mycophenolate, warfarin, some vaccines
Antimicrobial class: aminopenicillin
Pregnancy category: B
Average serum half life: 1.0
Biliary penetration: Therapeutic
CSF penetration: Therapeutic
Lung penetration: Therapeutic
Urine penetration: Therapeutic