Hospital Formulary Status Yes (PO solid, PO susp, parenteral inj)
In-Hospital Cost will be updated
PharmaCare Formulary Status Yes (PO solid, PO susp)
SA None
PharmaCare Coverage 250mg PO - $1.0163/tab 100mg/5ml PO susp recon - $0.4024/ml 200mg/5ml PO susp recon - $0.5702/ml
Outpatient Cost 250mg PO - $1.14-2.68/tab 600mg PO - $11.83-13.64/tab 100mg/5ml PO susp recon - $0.40-0.44/ml 200mg/5ml PO susp recon - $0.57-0.63/ml 500mg powder for soln/inj - $15.73-17.30/vial
Monitor QTc in patients with increased risk
Gastritis (PO and IV)
Hepatotoxicity (mainly with IV)
QT interval prolongation and CV mortality (PO and IV)
Hearing loss (mainly with IV)
Severe reactions (PO and IV)
Cancer relapse and death (mainly with IV)
Antimicrobial class: Macrolide
Pregnancy category: B
Very high tissue penetration and concentration intracellularly means in vivo activity may not be predicted by in vitro testing - i.e. Salmonella spp
Average serum half life: 68.0 hr
Biliary penetration: Therapeutic
CSF penetration: Poor
Lung penetration: Therapeutic
Urine penetration: Poor