Anaerobic spore forming Gram-positive bacilli, box-car shaped
Environmental (soil, water) organism as well as human/animal digestive tract.
Associated with penetrating wounds with environmental exposure
Gas gangrene/Clostridial myonecrosis
Necrotizing skin and soft tissue infection
Fatal bacteremia with massive exotoxin-mediated hemolysis
Foodborne self-limited gastrointestinal illness
Contact precautions while draining wound present.
Surgical debridement of devitalized tissue crucial.
IVIG and hyperbaric oxygen may be considered but lack of rigorous studies to support routine use.