Guidelines
Mild-moderate Post-Op IAI

Mild-moderate Post-Op IAI

Duration of Therapy

  • Patients with adequate source control procedure (e.g., surgery) who deffervesce, can have their antibiotics discontinued 4 days after the procedure.
  • Patients who do not have adequate source control or have retained hardware/mesh may require prolonged antibiotics (IV or oral) dependent on clinical and radiographic response. Consider expert consultation.

Anti-pseudomonal doses of Piperacillin/Tazobactam are not necessary empirically

Lack of treatment response is most often due to inadequate source control and not antibiotic failure. Consider expert consultation.

De-escalate

Vancomycin can be DISCONTINUED once E. faecium and MRSA are ruled out

Culture and sensitivities permitting,

SWITCH to:

AND

Oral Step-Down

Otherwise culture driven

Severe Beta-Lactam Allergy