Diagnosis of C. difficile disease requires careful clinical evaluation as testing is not as straightforward as for most other microbiologic conditions. The hallmark finding that is most associated with disease is presence of TOXIN in stool. However, TOXIN testing alone is not sensitive enough and patients with C. difficile disease may be TOXIN negative. This is the reason we perform two other tests. Both ANTIGEN and NAAT tests detect the presence of the organism in stool and are very sensitive. A negative result in either test rules out C. difficile.
Click here to see how we utilize and interpret these tests in Island Health.
Therapy decisions are based upon risk stratification and clinical progress. Click here for Therapy guidance.