Mild DFI: 1-2 weeks is usually sufficient

Moderate-severe DFI: 2-3 weeks

If osteomyelitis is diagnosed: 6 weeks


Treatment can be discontinued when signs and symptoms of infection have resolved. Antibiotics need not be
continued until the wound has fully healed

If patient undergoes surgical debridement, post-operative antibiotic duration is as follows:

  • Radical resection/amputation with no residual infection: 2-5 days post-operatively
  • Resection with residual infection: 4-6 weeks post-operatively