Cefdinir - Renal Dosing

In the setting of rapidly improving or worsening renal function, calculations of CrCl are inaccurate. Dosing should be based on estimated renal function instead.

If improving renal function, actual CrCl is likely higher than calculated CrCl.

If worsening renal function, actual CrCl is likely lower than calculated CrCl.

CrCl ≥30 mL/min

300mg PO Q12h or 600mg PO Q24h

CrCl <30 mL/min

300mg PO Q24h

300mg PO every other day (doses given on HD days should be given after HD)

300mg PO Q24h