Ceftolozane/Tazobactam

Restricted
C difficile risk
High
Oral Bioavailability
N/A
Cost
$$$$$$

Dosing

CrCl >50 mL/minCrCl 30-50 mL/minCrCl 16-30 mL/minCrCl ≤15 mL/min1.5g IV Q8h750mg IV Q8h375mg IV Q12hNo recommendations

Load 750mg IV, then 150mg IV Q8h

1.5g IV Q8h

General Information

Antimicrobial Stewardship approved criteria must be indicated at ORDER ENTRY.