Antimicrobial Stewardship approved criteria must be indicated at ORDER ENTRY.
Targeted or empiric therapy for gram positive infections including skin and soft tissue, and pneumonia.
Covers MRSA and VRE.
CBC at least once/week
Visual testing for therapy >3 months or if symptoms develop on therapy.
Elevated liver enzymes
Myelosuppression (usually with >2weeks therapy)- reversible
Peripheral/optic neuropathy with prolonged courses
SSRI and other serotonergics/MAOIs - Increased risk of serotonin syndrome.
Rifampin decreases linezolid levels.
Antimicrobial class: Oxazolidinone
Pregnancy category: C
Average serum half life: 5 hours
CSF penetration: Therapeutic
Lung penetration: Therapeutic
Urine penetration: Therapeutic