Non-Necrotizing Infection

Empiric Therapy

  • Loading dose of 20 mg/kg once is recommended

  • Q8h dosing is preferred in young adults

PLUS EITHER

OR

OR

Alternative (including for patients with severe penicillin allergy i.e. anaphylaxis, angioedema, hives, etc.)

De-escalation

De-escalate to narrower spectrum antibiotics based on rapid diagnostics and/or blood or tissue culture results