The score predicts probability of fluoroquinolone-resistant gram-negative bacilli in patients with bloodstream infections (BSI) and complicated urinary tract infections (cUTI).
It is particularly useful in patients with gram-negative BSI who have severe β-lactam allergy and in patients with acute pyelonephritis who do not otherwise require hospitalization.
Fluoroquinolones are not recommended for acute cystitis.
Dan S, et al. Antimicrob Agents Chemother 2016; 60: 2265-2272. doi: 10.1128/AAC.02728-15
Shah A, et al. Antimicrob Agents Chemother 2017; 61: e02313-16. doi: 10.1128/AAC.02313-16