Aerobic non-fermenting gram negative rod
May be acquired from diverse environmental sources (i.e. tap water).
Bronchiectatics may be colonized (i.e. CF patients).
Must distinguish colonization from clinically significant infection.
Most common reason for isolation is colonization of the respiratory tract.
Most common true infections - blood stream infection (usually from vascular catheter) and pneumonia.
Other manifestations rare (endocarditis, sinusitis, cellulitis, etc)
May require contact precautions
True pneumonia more likely in ICU and oncology patients, those with advanced age and after/during treatment with broad spectrum antimicrobial use.