Skin and Soft Tissue Infections


For severe or life-threatening infections, refer to PHC sepsis pathway (not in this app)

  • Non-purulent cellulitis is mostly caused by beta-hemolytic streptococci (e.g. Group A streptococci) or MSSA.

  • Purulent cellulitis can be caused by MRSA. Specimens should be obtained for microbiologic diagnosis.

  • Colonization with MRSA does NOT justify anti-MRSA treatment.

  • An important aspect of treatment is to keep the affected extremity elevated.

  • Improvement of erythema can take days, especially in patients with lymphedema.

  • 5 to 10 days of therapy is often adequate for the SSTI listed below.

  • Consider tetanus immunity status.