Loading dose 300mg IV infusion q12h on day 1
Followed by 300mg IV infusion q24h starting on day 2
NoteDelayed-Release TabletOral Suspension- Delayed release tablet and oral suspension are NOT bioequivalent; favour the delayed release tablet
No adjustment needed for renal impairmentLoading dose of 300mg PO q12h on day 1
Followed by 300mg PO q24h starting on day 2- Prophylaxis: 200mg PO three times daily
Treatment of invasive fungal infections: 400mg PO q12h OR 200mg four times daily for patients unable to tolerate a meal or nutritional supplement
IV: Accumulation and resultant toxicity of the diluent can occur if CrCl <50 mL/min
- Prophylaxis of yeast and mould infections in certain immunosuppressed patients.
- CYP450 inhibitor (3A4)
Available only from the desktop version of Spectrum through Horizon computers.