Posaconazole
Adult

Adult

Dosing Information

  • Delayed release tablet and oral suspension are NOT bioequivalent; favour the delayed release tablet
  • No adjustment required for renal impairment

IV

Loading dose 300 mg IV infusion q12h on day 1, followed by 300 mg IV infusion q24h starting on day 2

PO

Delayed-Release Tablet

Loading dose of 300 mg PO q12h on day 1, followed by 300 mg PO q24h starting on day 2

Oral Suspension

Prophylaxis: 200 mg PO q8h

Treatment of invasive fungal infections: 400 mg PO q12h OR 200 mg q6h for patients unable to tolerate a meal or nutritional supplement