End Stage Lung Disease

Microbiology

Based on patient evaluation, consider obtaining cultures before start of antimicrobial therapy and/or repeat if not improving after 72 hours of antimicrobial therapy

Treatment Considerations

Tailor antibiotic therapy for sputum culture results (past or current)

Dose adjustment required in renal impairment for all antimicrobials outlined below except cefTRIAXone

Oral Therapy

+/-

If Pseudomonas aeruginosa is suspected

OR

Alternative empiric regimen

Intravenous Therapy

Preferred empiric regimen

OR

Preferred empiric regimen if Pseudomonas aeruginosa is suspected

OR

Alternative empiric regimen

Duration

10-14 days