Fidaxomicin

C difficile risk
None
Oral Bioavailability
None
Cost
$189.20/day

Dosing

C. difficile
200mg po BID x 10days

No dosage adjustment necessary (minimal systemic absorption)

No supplemental doses required for HD

General Information

First line therapy for first episode or recurrent CDAD

NOTE: NLPDP and Eastern Health Criteria for use differ

See Eastern Health CDAD Treatment Guidelines for more information

C. difficile colitis

  • ¬†GI disturbance

  • ¬†Cytopenias

  • ¬†Hypersensitivity: facial, tongue or throat swelling

EH Prescribing Restrictions
None

NLPDP Status
Special Authorization required
More Information

See Eastern Health CDAD treatment guidelines for therapy recommendations.

SPECIAL AUTHORIZATION REQUIRED

Antimicrobial class: Specialized anti-C. difficile macrocyclic agent

Pregnancy category: B

Urine penetration: None

Lung penetration: None

CSF penetration: None

Biliary penetration: None